An der Schnittstelle von Biologie und Chemie widmet sich die Biochemie der Struktur und Funktion von Biomolekülen - mit zunehmender Bedeutung in der akademischen und kommerziellen Forschung. Dieses Werk eröffnet Studierenden ein Verständnis ihrer grundlegenden Prinzipien. "This excellent work fills the need for an upper-levelgraduate course resource that examines the latest biochemical,biophysical, and molecular biological methods for analyzing thestructures and physical properties of biomolecules... Thisreviewer showed [the book] to several of his senior graduatestudents, and they unanimously gave the book rave reviews. Summing Up: Highly recommended..." CHOICE Chemical biology is a rapidly developing branch of chemistry,which sets out to understand the way biology works at the molecularlevel. Fundamental to chemical biology is a detailed understandingof the syntheses, structures and behaviours of biologicalmacromolecules and macromolecular lipid assemblies that togetherrepresent the primary constituents of all cells and all organisms.The subject area of chemical biology bridges many differentdisciplines and is fast becoming an integral part of academic andcommercial research. This textbook is designed specifically as a key teachingresource for chemical biology that is intended to build onfoundations lain down by introductory physical and organicchemistry courses. This book is an invaluable text for advancedundergraduates taking biological, bioorganic, organic andstructural chemistry courses. It is also of interest to biochemistsand molecular biologists, as well as professionals within themedical and pharmaceutical industry. Key Features: A comprehensive introduction to this dynamic area of chemistry,which will equip chemists for the task of understanding andstudying the underlying principles behind the functioning ofbiological macro molecules, macromolecular lipid assemblies andcells. Covers many basic concepts and ideas associated with the studyof the interface between chemistry and biology. Includes pedagogical features such as: key examples, glossaryof equations, further reading and links to websites. Clearly written and richly illustrated in fullcolour.
? Essentials in Chemical Biology is a valuable resource notonly for chemistry students who are venturing into and interestedin biological systems, but also biochemistry and biology studentswho want a fundamental understanding of the physical and chemicalbasis of biology and the techniques used in its study.?( Chemistry World , August 2009) "The succinct and lucid presentation style of Essentials OfChemical Biology will likely make it a popular resource forundergraduate and graduate students interested in the structure andinteraction of biologically relevant macromolecules." ( Journalof Chemical Biology , February 2009) "This excellent work fills the need for an upper-level graduatecourse resource that examines the latest biochemical, biophysical,and molecular biological methods for analyzing the structures andphysical properties of biomolecules. Miller (Imperial CollegeLondon, UK) and Tanner (Univ. of Hong Kong) cover traditionalsubjects such as binding interactions and catalysis. They alsodescribe biophysical theories and current methods for proteinstructure determinations such as circular dichroism, X-raycrystallography, neutron diffraction, NMR, EPR, fluorescence, massspectrometry, and electron and atomic force microscopy. Forexample, the chapter on solution NMR provides simplified yethigh-quality explanations of the key principles of NMR. Thewell-developed introduction helps students to better follow themore complex information concerning the principles ofmultidimensional NMR. In addition, the latter part of the chapteroffers current applications using a variety of multidimensional NMRspectroscopy experiments in the analysis of proteins, nucleic acid,carbohydrate, and lipid structures. This reviewer showed Essentials of Chemical Biology to several of his seniorgraduate students, and they unanimously gave the book rave reviews.The work could be improved by better referencing the resourcematerials within the text and by providing student exercises at theend of each chapter. " ( J. M. Tomich, Kansas StateUniversity, Choice , February 2009)