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Produktbild: Hormonal Carcinogenesis III
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Hormonal Carcinogenesis III Proceedings of the Third International Symposium

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.11.2000

Herausgeber

Jonathan J. Li + weitere

Verlag

Springer Us

Seitenzahl

555

Maße (L/B/H)

3,2/16,3/24,3 cm

Gewicht

960 g

Auflage

2001 edition

Sprache

Englisch

ISBN

978-0-387-95127-0

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

21.11.2000

Herausgeber

Verlag

Springer Us

Seitenzahl

555

Maße (L/B/H)

3,2/16,3/24,3 cm

Gewicht

960 g

Auflage

2001 edition

Sprache

Englisch

ISBN

978-0-387-95127-0

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Hormonal Carcinogenesis III
  • Symposium Address Hormonal Carcinogenesis: Perceptions, Challenges, and Anticipations.- State Of The Art Lectures.- 1 The Numbers Game with Estrogen Receptors and Growth Regulation.- 2 Expression Genetics of Hormone Dependent Human Tumors.- 3 New Directions in Epidemiologic Studies of Hormonally-related Cancers.- 1. Epidemiology: Breast and Prostate Cancer.- 4 Estrogen Causes Breast Cancer: Increasing Duration of Use of Postmenopausal Hormones Increases the Risk of Breast Cancer.- 5 Frequency of BRCA2 Mutations in Women with Early Onset Breast Cancer Drawn from a Population-Based Study.- 6 Prostate Cancer, Androgens, and Estrogens.- 2. Molecular Genetics of Hormonal Cancers.- Breast Cancer Molecular Cytogenetics.- 7 Genome Scanning and Tissue Microarrays for the Analysis of Molecular Mechanisms Underlying Hormone Therapy Failure in Prostate Cancer.- 8 Serial Analysis of Gene Expression in Breast Cancer Cells.- 9 The Effects of Triphenylethylene Antiestrogens on Parameter of Multistage Hepatocarcinogenesis in the Rat.- 3. Estrogen Receptor Interactions.- The Curious Pharmacology of the Antiestrogens.- 10 Estrogen Receptor ?: An Important Player in Estrogen Action.- 11 Estrogen Receptor Mediated Genomic Instability in the Syrian Hamster Kidney: A Critical Event in Hormonal Oncogenesis.- 4. Estrogen/Progesterone - Breast Cancer.- Breast Cancer Prevention with Estrogen and Progesterone: Mimicking the Protective Effect of Pregnancy.- 12 The Dual Role of Estrogens and Cathepsin D in Invasion and Metastasis.- 13 Estrogen-induced Breast Cancer in Female ACI Rats.- 14. A Transgenic Mouse Model for Mammary Carcinogenesis.- 5. Cell Cycle, Cell Proliferation.- Receptor Tyrosine Kinases and the Effects of Ovarian Steroids on Cell Proliferation.- 15 Transcriptional Control of Cell Cycle Progression by Estrogenic Hormones: Regulation of Human Cyclin D1 Gene Promoter Activity by ER-?.- 16 Estrogen Regulation of Cell Cycle Progression.- 6. Oncogenes/Tumor Suppressor Genes.- 17 Estrogen and c-myc Protooncogene Actions in Human Breast Cancer.- 18 Steroid Hormone Regulation of Vascular Endothelial Growth Factor (VEGF) Production: A Potential Step in Hormonal Carcinogenesis.- 19 TGF-?/Estrogen-inducible Early Gene (TIEG): A Candidate Tumor Suppressor or Cell Cycle Regulator?.- 7. Aromatase: Implications For Breast Cancer.- Aromatase: Implications for Breast Cancer.- 20 Control of Estrogen Biosynthesis in Breast Cancer.- 21 Regulation of Aromatase in Normal and Malignant Breast Tissues: The Role of the Immune System.- 22 Regulation of Aromatase in Breast Cancer and Correlation of Aromatase and Cyclooxygenase Gene Expression.- 8. Organ Site: Prostate/Ovary.- Androgen Receptor and its Role in the Development and Control of Androgen-independent Prostate Cancer.- 23 Etiologic Mechanisms in Epithelial Ovarian Cancer.- 24 Stromal Influences in Prostatic Carcinogenesis.- 25 Androgen Receptor Structure and Function in Prostate Cancer.- 9. Osteoporosis and Estrogens.- Hormone Replacement Therapy: A Clinical Overview.- 26 Role of Estrogen and Bone Morphogentic Protein Signaling in Osteoblast Differentiation.- 27 Estrogens and the Skeleton.- 10. Cardiovascular Disease and Estrogens/Progestins.- 28 Mechanisms of Estrogen Action on the Cardiovascular System.- 29 Atherosclerosis and Hormone Replacement Therapy: The Role of Estrogen in Secondary Prevention of Cardiovascular Events.- Viewpoint.- 30 Long-term Hormone Replacement Therapy: A Contrary Point of View.- Epilogue.- 31 A Unified General Mechanism for Hormonal Carcinogenesis Begins to Emerge.- Communications.- Session I. Epidemiology/Human Studies.- The Risk of Postmenopausal Breast Cancer After Estrogen and Estrogen-Progestin Replacement.- No Significant Difference in Age at Menarche, Menstrual Cycle Length, Age at First Full Term Pregnancy, and Nulliparity among BRCA1 Mutation Carriers Compared with Their Unaffected Relatives.- Cell Proliferation and Apoptosis in the Normal Breast Epithelium of Pre, Peri, and Postmenopausal Women.- Expression and Estrogen Inducible Promoter Activity of Human Estrogen-responsive Finger Protein Gene in Breast and Ovarian Cancer Cells.- Novel Small Molecule IL-6 Inhibitors as Anti-Cancer Drugs.- Session II. Metabolism Studies/Cellular & Molecular Biology.- Cellular Transforming Activity and Genotoxic Effects of 17?-EstradioI and Its Eight Metabolites in Syrian Hamster Embryo Cells.- Evidence for an Initiation Mechanism of 17? Estradiol Carcinogenesis.- Estradiol Metabolism by Rat Liver Microsomes from Strains Differing in Susceptibility to Mammary Carcinogenesis.- Induction of Breast Cancer in Noble Rats with a Combination of Estrogen and Testosterone.- Isolation and Purification of Breast Carcinoma Cell Lines from a Noble Rat.- The ACI Rat as a Genetically Defined Animal Model for the Study of Estrogen Induced Mammary Cancers.- Characteristics of Dehydroepiandrosterone-induced Hepatocarcinogenesis in the Rat.- Hepatic Toxicity of Estrogen in Armenian and Chinese Hamsters.- Suppression of Liver Tumor Formation by the Liver Microenvironment of Female, but Not Male, Syngeneic Hosts.- Dietary Energy Restriction Inhibits Estrogen Induced Pituitary Tumorigenesis in a Rat Strain Specific Manner.- Estrogen-induced Prolactinoma Development: A Role for Cell-Cell Communication.- Combined Administration of Transplacental Ethylnitrosourea and Postnatal Diethylstilbestrol Induce Neural Differentiation in Interstitial Cells of the Golden Hamster Kidney.- Aromatase Overexpression: Is Aromatase an Oncogene?.- Genetic Toxicity In Vitro of Bisphenol A-Diglycidylether (BADGE) and its Hydrolysis Products.- Lack of Genotoxicity of Major Mammalian and Plant Lignans at Various Endpoints In Vitro.