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Produktbild: Molecular Toxicology Protocols
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Molecular Toxicology Protocols

Aus der Reihe Methods in Molecular Biology
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121,99 € UVP 139,05 €

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Abbildungen

115 SW-Abb., XIV, 490 p. 115 illus.

Herausgeber

Phouthone Keohavong + weitere

Verlag

Humana Press

Seitenzahl

490

Maße (B/H)

15,2/22,9 cm

Gewicht

1810 g

Sprache

Englisch

ISBN

978-1-58829-084-7

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Abbildungen

115 SW-Abb., XIV, 490 p. 115 illus.

Herausgeber

Verlag

Humana Press

Seitenzahl

490

Maße (B/H)

15,2/22,9 cm

Gewicht

1810 g

Sprache

Englisch

ISBN

978-1-58829-084-7

Herstelleradresse

Springer Heidelberg
Tiergartenstr. 17
69121 Heidelberg
DE
buchhandel-buch@springer.com

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  • Produktbild: Molecular Toxicology Protocols
  • Part I. Analysis of DNA Adducts
    32P-Postlabeling Analysis of DNA Adducts
    David H. Phillips, Alan Hewer, and Volker M. Arlt
    Modification of the 32P-Postlabeling Method to Detect a Single Adduct Species as a Single Spot
    Masako Ochiai, Takashi Sugimura, and Minako Nagao
    DNA Isolation and Sample Preparation for Quantification of Adduct Levels by Accelerator Mass Spectrometry
    Karen H. Dingley, Esther A. Ubick, John S. Vogel, and Kurt W. Haack
    Fluoroimaging-Based Immunoassay of DNA Photoproducts in Ultraviolet-B-Irradiated Tadpoles
    Iovanna Pandelova, Stephen R. Hewitt, and John B. Hays
    Analysis of DNA Strand Cleavage at Abasic Sites
    Walter A. Deutsch and Vijay Hegde
    Part II. Detection of Chromosomal and Genome-Wide Damage
    Premature Chromosome Condensation in Human Resting Peripheral Blood Lymphocytes for Chromosome Aberration Analysis Using Specific Whole-Chromosome DNA Hybridization Probes
    Pataje G. S. Prasanna and William F. Blakely
    Mutagen-Induced Chromatid Breakage as a Marker of Cancer Risk
    Xifeng Wu, Yun-Ling Zheng, and T. C. Hsu
    Flow Cytometric Analysis of Micronuclei in Erythrocytes, Jan Grawé
    The Comet Assay: A Sensitive Genotoxicity Test for the Detection of DNA Damage
    Günter Speit and Andreas Hartmann
    Computerized Image Analysis Software for the Comet Assay
    R. C. Chaubey
    The Comet-FISH Technique: A Tool for Detection of Specific DNA Damage and Repair
    Alexander Rapp, Michael Hausmann, and Karl Otto Greulich
    DNA Double-Strand Break Damage and Repair Assessed by Pulsed-Field Gel Electrophoresis
    Nina Joshi and Stephen G. Grant
    Part III. Detection and Characterization of Surrogate Gene Mutation
    Analysis of In Vivo Mutation in the Hprt and Tk Genes of Mouse Lymphocytes
    Vasily N. Dobrovolsky, Joseph G. Shaddock, and Robert H. Heflich
    Quantifying In Vivo Somatic Mutations Using Transgenic Mouse Model Systems
    Roy R. Swiger
    Methods for Detecting Somatic Mutations In Vitro: The Human T-Cell Cloning Assay Selecting for HPRT Mutants
    Sai-Mei Hou
    Molecular Analysis of Mutations in the Human HPRT Gene
    Phouthone Keohavong, Liqiang Xi, and Stephen G. Grant
    Simultaneous Quantification of t(14;18) and HPRT Exon 2/3 Deletions in Human Lymphocytes
    James C. Fuscoe
    The GPA In Vivo Somatic Mutation Assay
    Stephen G. Grant
    Flow Cytometric Measurement of Mutant T Cells With Altered Expression of TCR: Detecting Somatic Mutations in Humans and Mice
    Seishi Kyoizumi, Yoichiro Kusunoki, and Tomonori Hayashi
    Part IV. Detection and Characterization of Cancer Gene Mutation
    Mutation Screening of the TP53 Gene by Temporal Temperature Gradient Gel Electrophoresis
    Therese Sørlie, Hilde Johnsen, Phuong Vu, Guro Elisabeth Lind, Ragnhild Lothe, and Anne-Lise Børresen-Dale
    Analysis of K-RAS and P53 Mutations in Sputum Samples
    Weimin Gao and Phouthone Keohavong
    Allele-Specific Competitive Blocker-PCR Detection of Rare Base Substitution
    Barbara L. Parsons, Page B. McKinzie, and Robert H. Heflich
    Gel-Based Nonradioactive Single-Strand Conformational Polymorphism and Mutation Detection: Limitations and Solutions
    Vibhuti Gupta, Reetakshi Arora, Anand Ranjan, Narendra K. Bairwa, Dheeraj K. Malhotra, P. T. Udhayasuriyan, Anjana Saha, and Ramesh Bamezai
    Detection and Characterization of Oncogene Mutations in Preneoplastic and Early Neoplastic Lesions
    Toshinari Minamoto
    Detection of DNA Double-Strand Breaks and Chromosome Translocations Using Ligation-Mediated PCR and Inverse PCR
    Michael J. Villalobos, Christopher J. Betti, and Andrew T. M. Vaughan
    Part V. Analysis of DNA Repair Mechanisms
    Microsatellite Instability: An Indirect Assay to Detect Defects in the Cellular Mismatch Repair Machinery
    Anjana Saha, Narendra K. Bairwa, and Ramesh Bamezai
    Unscheduled DNA Synthesis: A Functional Assay for Global Genomic Nucleotide Excision Repair
    Crystal M. Kelly and Jean J. Latimer
    Analysis of DNA Repair Using Transfection-Based Host Cell Reactivation
    Jennifer M. Johnson and Jean J. Latimer
    An Immunoassay for Measuring Re