The Inflamed Mind: A Radical New Approach to Depression

Inhaltsverzeichnis

CONTENTS

List of Figures ix
Preface xi

One: Daring to think differently 1
Root canal blues
Neuro-immunology and immuno-psychiatry
What does an inflamed mind look like?
The revolution will not be televised

Two: The workings of the immune system 20
Inflammation and infection
Fig 1. Immune cells
Fig 2. Inflammation
Location, location, location
Communication: the medium is the message
Fig 3. The immune system
Rapid rebuttal and learning
Auto-immunity: the flip side

Three: Hiding in plain sight 43
It's depressing being ill
The cogito, God, and the machine
Fig 4. A lady trying to explain the pineal theory of the human mind and body
A long shadow
Mrs P is not alone
A bona fide blockbuster
The Cartesian blind spot

Four: Melancholia after Descartes 69
From black bile to MDD
A cross to bear
Super-shrink
Fig 5. Freud's first draft of the ego
Dancing in the sanatorium
Fig 6. First prophet of pharmaceuticals
The golden age
Fig 7. Scenes of joy at the dawn of anti-depressants
Fig 8. The seer and the synapse
Farcical serotonin
Bereft of biomarkers

Five: How? 112
Extraordinary claims demand extraordinary evidence
A stubborn fact
Causes must come first
The Berlin wall in the brain
Fig 9. What I was taught at medical school - and what we now know
Fig 10. Nervous reflex control of inflammation
Inflamed brains

Six: Why? 146
What could make you inflamed (and depressed)?
Flaming stressed
Causal chains and cycles
Ultimately, the answer must always be Darwin
Fig 11. Emotional faces and emotional brains
A savannah survival story

Seven: So what? 176
Medical apartheid
Fig 12. The vicious cycle of stress, inflammation and depression - and ways to break it - an artist's impression
Could it be different already?
Market failure
Beyond blockbusters: better but not bigger than Prozac
Alzheimer's disease and the yin and yang of microglia
Schizophrenia and auto-intoxication

References 221
Acknowledgements 229
Disclaimers 230
Index 231

The Inflamed Mind: A Radical New Approach to Depression

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Beschreibung

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Einband

Taschenbuch

Erscheinungsdatum

31.12.2019

Verlag

Picador

Seitenzahl

256

Beschreibung

Details

Einband

Taschenbuch

Erscheinungsdatum

31.12.2019

Verlag

Picador

Seitenzahl

256

Maße (L/B/H)

20,8/13,4/1,8 cm

Gewicht

210 g

Sprache

Englisch

ISBN

978-1-250-31816-9

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  • The Inflamed Mind: A Radical New Approach to Depression
  • CONTENTS

    List of Figures ix
    Preface xi

    One: Daring to think differently 1
    Root canal blues
    Neuro-immunology and immuno-psychiatry
    What does an inflamed mind look like?
    The revolution will not be televised

    Two: The workings of the immune system 20
    Inflammation and infection
    Fig 1. Immune cells
    Fig 2. Inflammation
    Location, location, location
    Communication: the medium is the message
    Fig 3. The immune system
    Rapid rebuttal and learning
    Auto-immunity: the flip side

    Three: Hiding in plain sight 43
    It's depressing being ill
    The cogito, God, and the machine
    Fig 4. A lady trying to explain the pineal theory of the human mind and body
    A long shadow
    Mrs P is not alone
    A bona fide blockbuster
    The Cartesian blind spot

    Four: Melancholia after Descartes 69
    From black bile to MDD
    A cross to bear
    Super-shrink
    Fig 5. Freud's first draft of the ego
    Dancing in the sanatorium
    Fig 6. First prophet of pharmaceuticals
    The golden age
    Fig 7. Scenes of joy at the dawn of anti-depressants
    Fig 8. The seer and the synapse
    Farcical serotonin
    Bereft of biomarkers

    Five: How? 112
    Extraordinary claims demand extraordinary evidence
    A stubborn fact
    Causes must come first
    The Berlin wall in the brain
    Fig 9. What I was taught at medical school - and what we now know
    Fig 10. Nervous reflex control of inflammation
    Inflamed brains

    Six: Why? 146
    What could make you inflamed (and depressed)?
    Flaming stressed
    Causal chains and cycles
    Ultimately, the answer must always be Darwin
    Fig 11. Emotional faces and emotional brains
    A savannah survival story

    Seven: So what? 176
    Medical apartheid
    Fig 12. The vicious cycle of stress, inflammation and depression - and ways to break it - an artist's impression
    Could it be different already?
    Market failure
    Beyond blockbusters: better but not bigger than Prozac
    Alzheimer's disease and the yin and yang of microglia
    Schizophrenia and auto-intoxication

    References 221
    Acknowledgements 229
    Disclaimers 230
    Index 231