Preface; Part I. Introduction: 1. Models of depression Steven P. Roose, Patrick J. McGrath and J. John Mann; 2. Diagnosis of mood disorders Michael B. First and Jean Endicott; 3. Dysthymia and chronic depression David J. Hellerstein and Jordan W. Eipper; Part II. Medical Management: 4. Management of adult major depressive disorder J. John Mann, Steven P. Roose and Patrick J. McGrath; 5. Atypical depression Jonathan W. Stewart; 6. Psychotic depression Barnett S. Meyers and Jimmy N. Avari; 7. Pharmacologic and somatic treatments for bipolar depression Lucas Giner, S. Aiden Kelly and Maria A. Oquendo; 8. Medication treatment of mania: acute and preventive David A. Kahn; 9. Treatment of mood disorders in later life Steven P. Roose and Devangere P. Devanand; 10. Chronic depression James H. Kocsis and Benjamin D. Brody; 11. Pediatric depression David A. Brent; 12. Therapeutics of pediatric bipolar disorder Robert A. Kowatch, Melissa P. DelBello and Barbara L. Gracious; 13. Depression in the context of physical illness Peter A. Shapiro, Philip R. Muskin and Emily Gastelum; 14. Mood disorders in the context of borderline personality disorder Eric A. Fertuck, Megan S. Chesin and Barbara H. Stanley; 15. Depression in the context of pregnancy Margaret G. Spinelli and Carolyn Broudy; 16. Depression and the menstrual cycle Benicio N. Frey, Luciano Minuzzi, Roberto Sassi and Meir Steiner; 17. Depression in the context of alcoholism and other substance use disorders Edward V. Nunes, Jr and Frances R. Levin; 18. Complementary and alternative treatments for mood disorders Drew Ramsey, M. Elizabeth Sublette and Philip R. Muskin; Part III. Psychotherapies for Mood Disorders: 19. Cognitive behavior therapy Michael E. Thase; 20. Interpersonal therapy Myrna M. Weissman, Annie E. Rabinovitch and Helena Verdeli; 21. Dialectical behavioral therapy for mood disorders Barbara H. Stanley and Megan S. Chesin; 22. The psychodynamic treatment of mood disorders Deborah L. Cabaniss, Diana E. Moga and Aerin M. Hyun; 23. Combining medication and psychotherapy in the treatment of depression Bret R. Rutherford and Steven P. Roose; Part IV. Specific Modalities of Treatment: 24. Electroconvulsive therapy Joshua Berman and Joan Prudic; 25. Transcranial magnetic stimulation and deep brain stimulation Sarah H. Lisanby and Moacyr A. Rosa; 26. Chronotherapeutics: light therapy, wake therapy, and melatonin Michael Terman and Jiuan Su Terman; 27. Ketamine in treatment-resistant depression Kyle Lapidus and Sanjay J. Mathew; Part V. The Promise of Biomarkers and Response Prediction: 28. Brain imaging Ramin V. Parsey and Martin J. Lan; 29. Pharmacogenetics and mood disorders Gonzalo Laje and Francis J. McMahon; 30. Electrophysiological predictors of clinical response to antidepressants Gerard E. Bruder, Craig E. Tenke and Jürgen Kayser; Part VI. Future Directions: 31. Future directions Patrick J. McGrath, Steven P. Roose and J. John Mann; Index.