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Produktbild: Advancement in CAR T-Cell Therapy in Tumors
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Advancement in CAR T-Cell Therapy in Tumors Current Challenges and Future Directions

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

03.01.2026

Abbildungen

XIX, 332 p. 28 illus., 27 illus. in color.

Herausgeber

Umesh Kumar + weitere

Verlag

Springer Singapore

Seitenzahl

332

Maße (L/B/H)

24,1/16/2,5 cm

Gewicht

692 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-981-9536-27-6

Beschreibung

Portrait


Dr. Umesh Kumar
is currently serving as Associate Director in Chandigarh University, Mohali, Punjab. He has been a Professor and Head, Research Cell in the Department of Biosciences at IMS Ghaziabad (University Courses Campus), Ghaziabad, Uttar Pradesh. He also worked as a Scientific Officer in the Department of Biochemistry at the University of Delhi. His research interests encompass a range of topics, including the molecular diagnosis of cervical cancer, the molecular epigenetics of breast carcinogenesis, CAR T-cell therapy, mesenchymal stem cells, epithelial ovarian carcinoma, and tumor virology. 





Dr. Anil Kumar
is presently working as Staff Scientist in the National Institute of Immunology, New Delhi. His research interest focuses on understanding the link between gut microbiota and human cancer as well as how the result of the investigation may be helpful to devise strategies to develop gut bacteria/metabolite-based adjuvant immunotherapy for the treatment of colorectal cancer.His research group is also working on exploring the anticancer potential of gut microbiota derived metabolites for cancer treatment. He had participated in the development of biosensors which have been transferred to industry. In 2012, one of his patents has been selected for CSIR Technology Award 2012 and other US patent won Merck Millipore India Innovation Award 2012.





Dr. Deepak Parashar
is an Assistant Professor in the laboratory of Siegfried Janz in the Division of Hematology and Oncology, Department of Medicine, at the Medical College of Wisconsin (MCW), Milwaukee. His long-term research interests involve the development of a comprehensive understanding of key developmental pathways and how alterations in gene expression contribute to human cancer. His academic training and research experience have provided him with an excellent background in multiple biological disciplines including molecular biology, biochemistry, and genetics. 

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

03.01.2026

Abbildungen

XIX, 332 p. 28 illus., 27 illus. in color.

Herausgeber

Verlag

Springer Singapore

Seitenzahl

332

Maße (L/B/H)

24,1/16/2,5 cm

Gewicht

692 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-981-9536-27-6

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: ProductSafety@springernature.com

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  • Produktbild: Advancement in CAR T-Cell Therapy in Tumors

  • Chapter 1: History and Evolution of CAR T-Cell Therapy.- Chapter 2: CAR T-Cell Therapy: Basic Principles and Mechanisms.- Chapter 3: Engineering CAR T-Cells: Advances in Vector Design and Gene Editing.- Chapter 4: Optimizing CAR T-Cell Efficacy: Enhancing Proliferation, Persistence, and Memory.- Chapter 5: Clinical Success of CAR T-Cells in Hematologic Cancers: Lessons from Leukemia and Lymphoma.- Chapter 6: Adverse Effects of CAR T-Cell Therapy and Management: Cytokine Release Syndrome and Neurotoxicity.- Chapter 7: Overcoming Challenges of CAR T-Cell Therapy in Solid Tumor Microenvironments.- Chapter 8: From Bench to Bedside: Innovations and Challenges in CAR-T Cell Therapy Manufacturing and Regulation.- Chapter 9: Combining CAR T Cells with Immunotherapies to Enhance Treatment Effectiveness.- Chapter 10: Next-Generation CARs and Beyond: Synthetic Biology and Logic-Gated in Next-Generation CARs.- Chapter 11: Regulatory landscape and challenges in CAR-T cell therapy development and clinical trials.- Chapter 12: Personalized CAR T-Cell Therapy: Tailoring to Patient-Specific Tumors.