New aspects of pathology in Parkinson’s disease with concomitant incipient Alzheimer’s disease.- New horizons in molecular mechanisms underlying Parkinson’s disease and in our understanding of the neuroprotective effects of selegiline.- Early diagnosis in Parkinson’s disease — limitation of biochemical markers and instrumental methods.- The pharmacology of B-type selective monoamine oxidase inhibitors; milestones in (−)-deprenyl research.- (−)-Deprenyl reduces neuronal apoptosis and facilitates neuronal outgrowth by altering protein synthesis without inhibiting monoamine oxidase.- Are metabolites of l-deprenyl (selegiline) useful or harmful? Indications from preclinical research.- Deprenyl in the treatment of Parkinson’s disease: clinical effects and speculations on mechanism of action.- 8The clinical potential of Deprenyl in neurologic and psychiatric disorders.- Pharmacology and neuroprotective properties of rasagiline.- Potential of neurotrophic factors in therapy of Parkinson’s disease.