Produktbild: Snyder and Champness Molecular Genetics of Bacteria

Snyder and Champness Molecular Genetics of Bacteria

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Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

27.10.2020

Verlag

John Wiley & Sons Inc

Seitenzahl

640

Maße (L/B/H)

28,2/21,2/3,6 cm

Gewicht

1974 g

Auflage

5th edition

Sprache

Englisch

ISBN

978-1-55581-975-0

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

27.10.2020

Verlag

John Wiley & Sons Inc

Seitenzahl

640

Maße (L/B/H)

28,2/21,2/3,6 cm

Gewicht

1974 g

Auflage

5th edition

Sprache

Englisch

ISBN

978-1-55581-975-0

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Snyder and Champness Molecular Genetics of Bacteria
  • Preface xv
     
    Acknowledgments xix
     
    About the Authors 1
     
    Introduction 3
     
    The Biological Universe 5
     
    The Bacteria 5
     
    The Archaea 7
     
    The Eukaryotes 7
     
    What is Genetics? 8
     
    Bacterial Genetics 8
     
    Bacteria Are Haploid 9
     
    Short Generation Times 9
     
    Asexual Reproduction 9
     
    Colony Growth on Agar Plates 9
     
    Colony Purification 9
     
    Serial Dilutions 9
     
    Selections 10
     
    Storing Stocks of Bacterial Strains 10
     
    Genetic Exchange 10
     
    Phage Genetics 10
     
    Phages Are Haploid 11
     
    Selections
     
    with Phages 11
     
    Crosses with Phages 11
     
    A Brief History of Bacterial Molecular Genetics 11
     
    Inheritance in Bacteria 11
     
    Transformation 11
     
    Conjugation 12
     
    Transduction 12
     
    Recombination within Genes 12
     
    Semiconservative DNA Replication 12
     
    mRNA 12
     
    The Genetic Code 12
     
    The Operon Model 12
     
    Enzymes for Molecular Biology 12
     
    Synthetic Genomics 13
     
    What is Ahead 13
     
    1 The Bacterial Chromosome: DNA Structure, Replication, and Segregation 17
     
    DNA Structure 17
     
    The Deoxyribonucleotides 17
     
    The DNA Chain 18
     
    The 5' and 3' Ends 18
     
    Base Pairing 20
     
    Antiparallel Construction 20
     
    The Major and Minor Grooves 21
     
    The Mechanism of DNA Replication 21
     
    Deoxyribonucleotide Precursor Synthesis 21
     
    Replication of the Bacterial Chromosome 21
     
    Replication of Double- Stranded DNA 26
     
    Replication Errors 30
     
    Editing 30
     
    RNA Primers and Editing 31
     
    Impediments to DNA Replication 31
     
    Damaged DNA and DNA Polymerase III 31
     
    Mechanisms To Deal with Impediments on Template DNA Strands 32
     
    Physical Blocks to Replication Forks 32
     
    Replication of the Bacterial Chromosome and Cell Division 32
     
    Structure of Bacterial Chromosomes 34
     
    Replication of the Bacterial Chromosome 34
     
    Initiation of Chromosome Replication 34
     
    RNA Priming of Initiation 35
     
    Termination of Chromosome Replication 35
     
    Chromosome Segregation 37
     
    Coordination of Cell Division with Replication of the Chromosome 47
     
    Timing of Initiation of Replication 49
     
    The Bacterial Nucleoid 51
     
    Supercoiling in the Nucleoid 51
     
    Topoisomerases 52
     
    The Bacterial Genome 55
     
    Box 1.1 Structural Features of Bacterial Genomes 37
     
    Box 1.2 Antibiotics That Affect Replication and DNA Structure 54
     
    2 Bacterial Gene Expression: Transcription, Translation, Protein Folding, and Localization 61
     
    Overview 61
     
    The Structure and Function of RNA 62
     
    Types of RNA 62
     
    RNA Precursors 62
     
    RNA Structure 62
     
    RNA Processing and Modification 64
     
    Transcription 64
     
    Structure of Bacterial RNA Polymerase 64
     
    Overview of Transcription 65
     
    Details of Transcription 67
     
    rRNAs and tRNAs 74
     
    RNA Degradation 77
     
    RNases 77
     
    The Structure and Function of Proteins 78
     
    Protein Structure 78
     
    Translation 80
     
    Structure of the Bacterial Ribosome 80
     
    Overview of Translation 83
     
    Details of Protein Synthesis 84
     
    The Genetic Code 92
     
    Polycistronic mRNA 96
     
    Protein Folding and Degradation 98
     
    Protein Chaperones 98
     
    Protein Degradation 101
     
    Protein Localization 101
    &nb