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Produktbild: Alzheimer’s Disease Research
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Alzheimer’s Disease Research What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift

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Beschreibung

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

15.07.2024

Abbildungen

XXV, 652 p. 116 illus., 107 illus. in color.

Verlag

Springer

Seitenzahl

652

Maße (L/B/H)

23,5/15,5/2,7 cm

Gewicht

1136 g

Sprache

Englisch

ISBN

978-3-031-31572-5

Beschreibung

Rezension

“The depth of facts and explanatory figures will enlighten experts in Alzheimer’s disease (AD) research, students, and journalists. We know of no other work that reaches the scope of scholarship of this volume.” (George Perry and Rudolph Castellani, Journal of Alzheimer's Disease, June 20, 2024)


“This book ... represents a tour de force of almost 700 pages written by a leading contributor to the field over the last three decades, Christian Behl. ... The text is extremely thoroughly referenced, and the author describes his literature research process in detail.” (Anthony J. Turner, Journal of Neurochemistry, October 14, 2023)

Produktdetails

Einband

Taschenbuch

Erscheinungsdatum

15.07.2024

Abbildungen

XXV, 652 p. 116 illus., 107 illus. in color.

Verlag

Springer

Seitenzahl

652

Maße (L/B/H)

23,5/15,5/2,7 cm

Gewicht

1136 g

Sprache

Englisch

ISBN

978-3-031-31572-5

Herstelleradresse

Springer-Verlag KG
Sachsenplatz 4-6
1201 Wien
AT

Email: ProductSafety@springernature.com

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  • Produktbild: Alzheimer’s Disease Research

  • Chapter 1. Introduction.- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings.- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement.- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies.- Chapter 5. Focus on Neurochemistry Led to the
    Cholinergic Hypothesis
    of Alzheimer’s Disease.- Chapter 6. The
    Glutamatergic-Hypothesis
    of Alzheimer’s Disease.- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease.- Chapter 8. Getting to the Bottom of It:  Amyloid Beta Peptide Is Derived from a Larger Precursor.- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease.- Chapter 10. Concerns about the
    Amyloid Cascade Hypothesis
    and Reappraisals.- Chapter 11. Ignorance or Conspiracy? Or Just an
    Amyloid Firewall
     that Blocks Alternative Ideas?.- Chapter 12. In the Slip Stream of Amyloid: The
    Tau and Tangle Hypothesis
    .- Chapter 13. Focus on Tauopathies and Beyond.- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out.- Chapter 15. The
    Amyloid Cascade Hypothesis
    Has to Deliver, Finally.- Chapter 16. Beyond
    APP
    ,
    PSEN1
    ,
    PSEN2
    , and
    APOE
    :  What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way.- Chapter 18. Is the Persistence of the
    Amyloid Cascade Hypothesis
    a Result of Constant Confirmation Bias?.- Chapter 19. Driving Forces of Alzheimer’s Research Directions.- Chapter 20. Thirty Years after the Launch of the
    Amyloid Cascade Hypothesis
    : Is There a Shift of Gears at Last?.- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".